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Hyperrho

Product SpecsDescription
Manufacturer NameGrifols
Indications

Mini-Dose
For prevention of isoimmunization in Rho(D) negative women at the time of spontaneous or induced abortion of up to 12 weeks’ gestation.

Full Dose
For prevention of Rh hemolytic disease of the newborn by its administration to the Rho(D) negative mother within 72 hours after birth of an Rho(D) positive infant, and to prevent isoimmunization in Rho(D) negative individuals who have been transfused with Rho(D) positive red blood cells or blood components containing red blood.

ContraindicationsNone known. Rho(D) Immune Globin (Human) should be given with caution to patients with a history of prior systemic allergic reactions following the administration of human immune globulin preparations
Viral Safety ProcessPrecipitation, depth filtration, solvent/detergent treatment. The final container incubation step used during the manufacture of HyperRho S/D contributes to virus inactivation.
Route of AdministrationIntramuscular
Clearance of Rh-positive Red Blood Cells

Mini-Dose
Each single dose syringe contains sufficient anti-Rho(D) to effectively suppress the immunizing potential of 2.5 mL of Rho(D) positive packed red blood cells or the equivalent of whole blood (5 mL).

Full Dose
Each single dose syringe contains sufficient anti-Rho(D) to effectively suppress the immunizing potential of 15 mL of Rho(D) positive red blood cells.

Product Half-LifeApprox. 23-26 days
Latex ContentHyperRhO S/D mini-dose and HyperRho S/D full dose prefilled disposable syringes in a latex-free delivery system.
Thimerosal ContentNo
Storage Requirements/Shelf Life
  • Refrigerate at 2°C-8°C (36°F-46°F).
  • Do not freeze.
  • Do not use past expiration date listed on label.
Supply MethodPreservative (thimerosol)-free, prefilled disposable syringes with attached UltraSafe Needle Guard in a latex-free delivery system
Available SizesMini-Dose: 250 IU prefilled disposable syringe in 10pk
Full Dose: 1500 IU prefilled disposable syringe in 10pk and single syringe